Fundamentals of Antimicrobial Chemotherapy

Learning Objectives By the end of this section, you will be able to: Several factors are important in choosing the most appropriate antimicrobial drug therapy, including bacteriostatic versus bactericidal mechanisms, spectrum of activity, dosage and route of administration, the potential for side effects, and the…

Introduction

Figure 14.1 First mass produced in the 1940s, penicillin was instrumental in saving millions of lives during World War II and was considered a wonder drug.1 Today, overprescription of antibiotics (especially for childhood illnesses) has contributed to the evolution of drug-resistant pathogens. (credit…

Summary

13.1 Controlling Microbial Growth 13.2 Using Physical Methods to Control Microorganisms 13.3 Using Chemicals to Control Microorganisms 13.4 Testing the Effectiveness of Antiseptics and Disinfectants

Introduction

Figure 13.1 Most environments, including cars, are not sterile. A study1 analyzed 11 locations within 18 different cars to determine the number of microbial colony-forming units (CFUs) present. The center console harbored by far the most microbes (506 CFUs), possibly because that is…