Learning Outcomes By the end of this section, you should be able to: AChE Inhibitors AChE inhibitors bind to and interfere with the enzyme AChE. This enzyme is responsible for the destruction of ACh. By inhibiting this enzyme, more internally released…
Learning Outcomes By the end of this section, you should be able to: Alzheimer’s disease (AD) is the most common neurodegenerative condition of the brain and is characterized by significant changes in brain tissue. This disease is the most frequent cause…
Learning Outcomes By the end of this section, you should be able to: Cholinergic agonists are also termed parasympathomimetics, and cholinergic antagonists (also known as anticholinergics) are termed parasympatholytics. (The anticholinergic agents will be discussed in Drugs to Treat Parkinson’s Disease and Multiple Sclerosis.)…
Learning Outcomes By the end of this section, you should be able to: Myasthenia gravis (MG) is a progressive autoimmune neuromuscular disorder characterized by fluctuating muscle weakness and the onset of rapid fatigue. This disease does not discriminate based on gender,…
Figure 10.1 The nervous system, the body’s control center, consists of the brain, the spinal cord, and a complex system of nerves. (attribution: Copyright Rice University, OpenStax, under CC BY 4.0 license) Chapter Outline 10.1 Introduction to Myasthenia Gravis 10.2 Cholinergic Drugs 10.3 Introduction to…
This chapter discussed the causes and development of cancer based on different theories of mutational changes. These changes included the influences of stress, genetics, and environmental exposures as causes of cancer formation. The chapter also covered how chemotherapy works and…
Learning Outcomes By the end of this section, you should be able to: Monoclonal Antibodies and PD-1 Inhibitors Cancer therapy has experienced an explosion of new treatments with the development of biologics. Monoclonal antibodies are a type of biologic response modifier used…
Learning Outcomes By the end of this section, you should be able to: Antiestrogen Medications Antiestrogens, or estrogen antagonists, are a group of medications used to block estrogen receptors. By blocking these receptors, cancer cells that require estrogen for growth…
Learning Outcomes By the end of this section, you should be able to: Handling of Chemotherapeutic Agents The complexity of administering chemotherapy and caring for clients that have been treated with cancer therapies requires advanced knowledge. Special training and certifications to administer…
Learning Outcomes By the end of this section, you should be able to: Cancer Development Each day, the human body experiences cell mutations that result in a change in cellular structure, which may lead to cancer development. When this happens, the intracellular machinery may…