- In most cases, mesothelioma symptoms will not appear in an individual exposed to asbestos until many years (often 20-50 years) after the exposure has occurred.
- The symptoms, once evident are similar to other lungs and gastrointestinal cancers.

Pleural mesothelioma
- Chest pain
- Shortness of breath
- Dry cough
- Pleural efflusions
- Bloody sputum (If tumours invades into blood vessels)
- Occasionally destruction of lung tissue between bronchial tree and pleural space
- Fatigue
- Hoarseness
- Hypoxemia – low oxygen level
- Dysphasia – difficulty swallowing
- Fever/night sweats
Peritoneal mesothelioma
- Abdominal/stomach pain
- Ascites/swelling
- Anorexia/weight loss
- Nausea
- Anemia
- Thrombosis – blood clots
- Peritoneal effusion – fluid buildup
- Fever
- Hypoglycemia – low blood sugar
Pericardial mesothelioma
- Chest pain
- Pericardial effusion (fluid buildup)
- Arrhythmia
- Heart murmurs
- Fever/night sweats
- Coughing
- Dyspnea – shortness of breath
- Pulse variance
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